Asif Shahriar
Department of Microbiology, Stamford University Bangladesh, Dhaka, Bangladesh.
Title: Biofilm Formation and Antimicrobial Susceptibility Pattern of ESBL and Non-ESBL Producing Uropathogenic Bacteria
Biography:
I am Asif Shahriar and I am BSc final year student from Department of Microbiology at Stamford University, Bangladesh
I am a microbiologist with extensive laboratory experience, particularly in the
field of Clinical Microbiology the identification and function of model
organisms. I have published 2 Research Articles in reputed journals. I am the First Author and Md. Emam Hasan is the 2nd Author. We worked hard to finish the Project together. And Talha Bin Emran is our corresponding author, he has helped us to the entire project.
Abstract:
Urinary tract infections (UTIs) are the most common bacterial infection encountered worldntswide and are associated with significant morbidity and mortality. are the common bacterial pathogens that cause UTIs. The bacterial pathogens show resistance to most prescribed antibiotics to combat a variety of UTI infections. The present study was undertaken to investigate the biofilm forming ability, antibiotic susceptibility patterns and extended spectrum β lactamase (ESBL) production of seven uropathogenic isolates comprising both Escherichia coli and Klebsiella. pneumoniae. The strains were found to be multidrug resistant. The antimicrobial susceptibility profiles obtained in this study showed that the most active drug gentamicin, amikacin and imipenem (100% sensitivity) followed by Amoxicillin-clavulanic acid (85% sensitivity), Co-Trimoxazole, ciprofloxacin (57% sensitivity) ceftazidime and kanamycin (50% sensitivity). All the isolates showed resistance to amoxicillin followed by ceftriaxone and cefotaxime (71% resistance). The scenario gets more complicated due to production of ESBL by five isolates (three E.coli isolates, and two K. pneumoniae). The isolates were also able to form biofilm as tested on congo red agar medium and by microtiter plate assay. The findings of the study indicate that the emergence and rapid spread of such multidrug resistant pathogens are of great concern. Early detection of ESBL producing pathogen is of paramount clinical importance, therefore strict infection control practices as well as therapeutic guidance for confirmed infection can be rapidly initiated.